品悅牙醫診所（苗栗）

「We envision that it would be an ideal alternative for patients who pursue esthetic orthodontic treatment but were not likely to take lingual appliances or clear aligners.」

「Clear aligners have become a treatment alternative to metal brackets in recent years due to the advantages of aesthetics, comfort, and oral health improvement.」

「To evaluate the facial aesthetic effects of orthodontic treatment performed with clear aligners and to compare it to an untreated control group, on lower third facial ageing in adult patients through the use of the Wrinkle Severity Rating Scale (WSRS) at the beginning (T0) and at the end (T1) of the study period.」

「The greatest demand for orthodontic treatments comes from women, as they pay more attention to aesthetics, which makes the clear aligners the most common choice.」

「Despite their need of orthodontic treatment, they want to have an aesthetic alternative, as "invisible" as possible--something that can be achieved with the lingual technique.」

「With the advent of advanced appliances such as ceramic brackets, lingual braces, and clear aligners, alongside a growing emphasis on aesthetics and self-image, orthodontic care has become increasingly relevant for adults.」

「In contemporary dental care, an increasing number of adult patients are now seeking orthodontic treatment with the primary motive of improvement in appearance and achievement of esthetic smile.」

「Clear aligner is an advanced orthodontic method with benefits of comfort, aesthetics, and convenience.」

「There was no association between sex, previous orthodontic treatment history, satisfaction with own dental appearance and potential interest in treatment and aligner visibility and willingness-to-pay.」

「The precision of a 3D-printed dental model mainly relied on characteristics of photocurable resin, the resolution of light source and the exposure condition, which determined the eventual shape of the molded clear aligner and thus the orthodontic treatment efficacy.」

「This systematic review evaluates the effectiveness of artificial intelligence (AI) models in dental implant treatment planning, focusing on: 1) identification, detection, and segmentation of anatomical structures; 2) technical assistance during treatment planning; and 3) additional relevant applications.」

「Rehabilitation of a single missing tooth using a dental implant, although often considered less complex, presents unique clinical challenges and limitations.」

「AI-based implant planning may serve as a supportive tool under clinician supervision, potentially improving workflow efficiency and contributing to more standardized implant treatment planning as the technology advances.」

「This retrospective study investigates the diagnostic rationale for the extraction of teeth and their replacement with implants in a dental school setting.」

「Dental implant surgery has become a prevalent treatment option for patients with single tooth defects.」

「Dental implants have recently become established as a standard treatment protocol for replacing missing teeth.」

「Understanding these factors will help improve treatment planning and enhance implant success rates.」

「Even though dental surgery is an effective method of oral rehabilitation, it is imperative to individualize treatment planning and, especially in patients under anticoagulant therapy, to initiate early intervention in the prevention and management of hemorrhagic complications.」

「Diagnosis and treatment planning for dental implants has dramatically improved over the past three decades.」

「MRI and ultrasonography offer reliable non-ionizing alternatives for dental implant planning, with MRI matching CBCT in hard-tissue accuracy and ultrasonography excelling in soft tissue assessment.」

「Orthodontic consequences of early tooth loss include tipping and rotation of adjacent teeth and overeruption of opposing teeth.」

「The need for treatment in cases of missing teeth may result from aesthetic demands or functional impairment, although tooth loss itself does not necessarily constitute a need for prosthetic replacement.」

「Improper tooth alignment due to crowding, malocclusion, and missing teeth can cause difficulties with eating and speech, and premature wear.」

「The specialist dentist SSO for Reconstructive Dentistry is the expert for the rehabilitation of teeth after tooth loss.」

「A girl aged 13 years 10 months presented to an orthodontic department, complaining of missing teeth and poor dental aesthetics.」

「However, the number of missing teeth was significantly lower in the early orthodontic intervention group than in the control group (χ²=3.96, P=0.047).」

「Age and the number of missing teeth may be key factors on self-perceived OHRQoL in adult patients seeking orthodontic treatment.」

「Although management guidelines for traumatized teeth have been outlined, tooth loss following trauma is occasionally unavoidable.」

「The primary outcome was tooth loss.」

「Information obtained included age, gender, missing and extracted teeth, and reasons for extraction/tooth loss.」

「This review explores various orthodontic techniques, including fixed braces, maxillomandibular fixation (MMF), functional orthodontic therapy (FOT), and acrylic splints, emphasizing their roles in stabilizing fractures and promoting healing.」

「The aim of this study was to investigate the relationship between strain and elastic recovery of the aligner.」

「LIPUS also addresses orthodontically induced inflammatory root resorption, promoting the repair of cementum and reducing root damage through mechanisms involving osteoprotegerin and receptor activator of nuclear factor kappa-ligand signaling.」

「This experimental study evaluated the veterinary application of the Exogen LIPUS device in promoting alveolar bone healing and reducing post-orthodontic relapse in rabbits.」

「This study aims to evaluate the safety margin of the osseointegration of orthodontic implants by investigating the healing process of the implant-bone interface through histopathological studies and quantitative determination.」

「The affected tooth suddenly displayed crown discoloration and had no response to pulp testing at 6 weeks after the placement Invisalign Clear Aligner appliances.」

「The aim of this study was to investigate the dynamics of alveolar bone formation and healing pattern after the removal of orthodontic temporary anchorage devices (TADs).」

「In the first phase, orthodontic treatment with clear aligners (Invisalign) was applied to align the teeth in the maxillary arch to their ideal positions.」

「With the advent of clear aligner orthodontics, the clear versions of orthopedic modalities, namely, S8, S9 and S10, are specifically designed to alleviate mandibular displacement, therefore escalating the treatment efficacy by repositioning the mandible and correcting the individual teeth simultaneously.」

「To treat the concomitant mandibular defect and secondary dentomaxillofacial deformity, a hierarchical algorithm using orthodontics, orthognathic surgery, and fibula free flap was developed.」

「The effect of scaling and root planing (SRP) on the success of root canal-treated teeth with periodontal pockets is of interest.」

「The management of periodontal diseases has traditionally centered on mechanical debridement through scaling and root planing, a cornerstone of periodontal therapy.」

「This study aimed to comparatively evaluate the clinical outcomes of two therapies used in the management of periodontal conditions, represented by scaling and root planing (SRP) alone and laser-assisted new attachment procedure (LANAP).」

「The samples were divided into three groups: GROUP - A: only scaling and root planing (SRP), GROUP - B: SRP + 24% EDTA, GROUP - C: SRP + 0.2% hyaluronic acid.」

「Extensive reviews on the role of scaling and root planing (SRP) in the treatment of periodontitis have been previously published.」

「Removal of this infected cementum via scaling and root planing (SRP) was considered essential for re-establishing periodontal health.」

「To evaluate the efficacy of scaling and root planing (SRP) with a periodontal endoscope in the treatment of residual pockets in patients with periodontitis after initial periodontal therapy.」

「The aim of this work is to assess the structural gingival changes in patients with generalized chronic periodontitis (GCP), before and after scaling and root planing (SRP) by using fractal and multifractal analysis.」

「Ninety-five dental hygienists (59 dental clinics) were randomly assigned to one of two treatment protocols: (i) establishment of adequate self-performed oral hygiene prior to a single session of ultrasonic instrumentation (guided periodontal infection control [GPIC]) or (ii) conventional non-surgical therapy (CNST) including patient education and scaling and root planing integrated in multiple sessions.」

「Systematic review and meta-analysis on the nonsurgical treatment of chronic periodontitis by means of scaling and root planing with or without adjuncts.」

「Achieved transverse dentoalveolar expansion with clear aligners was lower than planned, particularly posteriorly and at gingival levels.」

「This review highlights the history of fabrication of clear aligners, examining the efficacy, advantages, and disadvantages of transparent aligners for pediatric patients and also dentists.」

「It was highlighted that the clear aligners had potential and were preferred for the adolescent orthodontic treatment.」

「Background and aim Orthodontic treatment has traditionally been associated with children and adolescents, as growth potential and skeletal adaptability were believed to optimize treatment outcomes.」

「This new theory of "early dental alveolar bone and dental arch remodeling technique" was proposed by Professor Li Xiaobing of the Department of Pediatric Dentistry, Faculty of Pediatric Dentistry and Orthodontics in West China Hospital of Stomatology through his clinical analyses and investigation of his early orthodontic interceptive treatments.」

「This study aimed to quantitatively and systematically evaluate the association between parent-child relationship (PCR) and orthodontic compliance with clear aligners (CAs) among children and adolescents.」

「Normative treatment need was assessed by the Dental Health Component (DHC) and the Aesthetic Component (AC) of the Index of Orthodontic Treatment Need (IOTN).」

「This study investigates the effects of interceptive orthodontics on dental and skeletal development in children with mixed dentition, aiming to evaluate the potential benefits of early orthodontic treatment.」

「This prospective study aimed to evaluate periodontal inflammation in adolescents undergoing orthodontic treatment with clear aligners (Invisalign® Teen, Align Technology, San Jose, CA, USA).」

「During clear aligner orthodontic treatment, adolescents are more prone to developing gingivitis than adults.」

「Dental implants are a reliable treatment option for restoring missing teeth, but adequate bone quantity and quality are crucial for success.」

「Dental implants have been used to restore missing teeth for several decades.」

「Resorption following tooth loss often presents challenges to both functional and esthetic outcomes of dental implant treatment for lost dentition, especially in the esthetic zone.」

「From three RCTs which compared early loading with conventional loading, there is insufficient evidence to determine whether or not there is a clinically important difference in prosthesis failure, implant failure or bone loss.」

「STATEMENT OF SIGNIFICANCE: With the high incidence of dental implants/fixtures for missing teeth, the success of the surgical procedures in restorative dentistry is dictated by the quality and quantity of the supporting alveolar bone.」

「Faced with the need to replace missing teeth, especially when it comes to dental implants, the lack of supporting tissues can compromise their correct positioning, leading to negative impacts on the success and longevity of the treatment.」

「Dental implants are being utilized by numerous dentists to replace missing teeth by restoring the function of teeth without compromising the aesthetics.」

「Dental implants are an important option for replacement of missing teeth.」

「Implant planning met 100% buccolingual/proximal/distal bone volume criteria and 90% sinus/canal distance criteria.」

「Prosthesis for missing maxillary molars with dental implants often requires maxillary sinus augmentation owing to insufficient alveolar bone height.」

「This study investigated the effects of different mini-screw anchorage techniques on the three-dimensional (3D) movement of anterior and posterior teeth during maxillary anterior retraction with clear aligners in extraction cases, aiming to provide guidance for clinical orthodontic practice.」

「Clear aligner therapy has expanded substantially in mixed dentition, yet the boundaries of clinical predictability across indications, movement types, and growth stages remain incompletely defined.」

「To analyse through a systematic review the effectiveness of clear aligners by assessing: (a) predictability of clear aligners and (b) treatment outcome comparison of clear aligner therapy with fixed appliance therapy.」

「The content of the guidelines is based on monographs and literatures on the clear aligner orthodontic treatment in the past five years, and the clinical consensus of all the members of Expert Group for Writing Project of Clear Aligner Technology.」

「"Guidelines for clear aligner orthodontic treatment (2021)" proposes clinical treatment recommendations in terms of practitioner requirements, clinical risks, diagnosis, treatment plan, and common clinical strategies for the orthodontic clear aligners technology.」

「An internet search reveals at least 27 different clear aligner products currently on offer for orthodontic treatment.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「Correcting malocclusions with controlled dental displacement is one of the objectives of orthodontic treatment.」

「The study, based on the modified Delphi method, collected the opinion of experts, comparing it with the scientific literature to evaluate the potential and limitations of orthodontic aligners, obtaining 47 consensus statements related to biomechanics and extraclinical factors.」

「Clear aligner therapy (CAT) has rapidly evolved as a preferred orthodontic treatment option due to its aesthetic appeal, comfort, and removability.」

「They result in both quantitative and qualitative changes in dental plaque, exposing orthodontic patients to dental caries and periodontal diseases.」

「During the orthodontic treatment, children with dentoalveolar anomalies are at high risk of dental caries and periodontal disease.」

「According to data provided by the World Health Organization (WHO), malocclusions represent the third most widespread oral health problem, after dental caries and periodontal diseases.」

「Fixed appliances, functional devices and, more recently, clear aligners have been associated with several oral health conditions, including enamel demineralization, dental caries, gingivitis, periodontitis and root and bone resorption.」

「Dental therapy involved the control of dental caries, periodontal disease, and opportunistic fungal infections and the use of fluoride-rich solutions.」

「Current evidence indicates that patients with stage IV periodontal disease can safely proceed with orthodontic treatment following active periodontal therapy.」

「However, the early stage caries, a most common complication in patients receiving orthodontic treatment using fixed appliances, has become a serious challenge to the prevention of dental caries and the esthetic outcome of orthodontic treatment.」

「Malocclusion is one of the most serious oral problems following dental caries and periodontal disease.」

「The aim of this study was to determine the relationship of orthodontic malocclusion with periodontal status, dental caries, and sociodemographic status.」

「Sixty-four percent of persons had periodontal disease, 21% had severe periodontal disease, and 29% had dental caries.」

「The present study was designed to compare root surface characteristics following root planing with hand and power-driven instruments.」

「Although subgingival scaling and root planing (SRP) are the "gold standard" treatment for periodontitis, these processes may remove excessive cement, exposing dentin and causing hypersensitivity, or producing defects such as ridges and grooves, leaving residual calculus and preventing access to the whole of the root surface.」

「To determine the preventive effect of a periodontal dressing containing colophony, zinc oxide and magnesium oxide applied after scaling and root planing on clinical variables, subgingival bacteria and local immune response in patients with chronic periodontitis.」

「The trial compared scaling and root planing (SRP) with community care for a follow-up period of six to 25 months.」

「Initial non-surgical periodontal therapy primarily consists of home care review and scaling and root planing.」

「Plasma samples were collected and quantified at baseline and 12 weeks after scaling and root planing (SRP) for Hcy using High Performance Liquid Chromatography with fluorescent detection (HPLC-fld).」

「The trial compared scaling and root planing (SRP) with community care for a follow-up period of six to 25 months.」

「Mechanical removal of gingival irritants by scaling and root planing combined with adjunctive antimicrobial therapy are first-line treatment options.」

「Periodontal treatment in irradiated patients mostly includes scaling and root planing, extraction of condemned teeth and topical and systemic antimicrobial therapy.」

「One hundred individuals will be allocated to test (intensive periodontal treatment comprised by scaling and root planing) or control (community periodontal treatment consisting of one session of supragingival plaque removal only) treatment groups.」

「We evaluated anxiety, pain, and oral-health-related quality of life in individuals treated with conventional fixed appliances (Group A) and clear aligners (Group B) for moderate malocclusion during the initial phase of orthodontic treatment.」

「The objective is to know the degree of anxiety and the factors associated with this anxiety during orthodontic treatment.」

「Different methods have been proposed for the classification of the dental anxiety scales and orthodontic pain as a first approach in the treatment process.」

「Dental anxiety is strongly associated with pain in orthodontic patients receiving clear aligners.」

「This study aimed to compare pain perception, anxiety, and impacts on oral health-related quality of life (OHRQoL) between adult patients receiving clear aligners and fixed appliances during the initial stage of orthodontic treatments.」

「This prospective study explored the impact of aligners on the oral health-related quality of life and anxiety of patients during the first month of orthodontic treatment and the first month of the retention phase.」

「Clinical findings suggest that orthodontic treatment with clear aligners (clear aligner therapy/CAT) may cause masticatory muscle soreness in some patients.」

「Almost every orthodontic patient had to stop attending their appointments, which put them in complicated situations and in fear of delayed treatment.」

「More than a half of the patient had average level of situational anxiety during orthodontic treatment.」

「To discuss the relationships between the level of anxiety, depression and perfectionism in dental patients before orthodontic treatment.」

「Edentulism conducts to a recognized impairment of oral function with both aesthetic and psychological changes.」

「Oral function was studied based on mastication, pronunciation, and use of dentures, and oral health behavior included brushing teeth after breakfast, after lunch, after dinner, and before sleep).」

「Background Dentures are one of the main treatments dentists deliver to restore the oral function and aesthetics of individuals with missing teeth.」

「In the meta-analysis, general patient satisfaction was significantly increased (p < .05), and the improved mastication was remarkable oral function.」

「Mouth rehabilitation with removable complete dentures decreased oral discomfort and, depending on the oral function, decreased or increased EMG activity of the orbicularis oris muscle.」

「Good oral health in old age is particularly important for maintaining adequate oral function, preventing pain and discomfort, controlling localized or systemic inflammation, sustaining social interaction, and preserving quality of life.」

「An oblique rotation of this solution revealed four highly correlated factors that we named Oral Function, Oro-facial Pain, Oro-facial Appearance and Psychosocial Impact.」

「Although the use of removable dentures can improve oral function and esthetics for elderly people, compared to those who do not wear removable dentures, those wearing removable dentures could have worse oral health related-quality of life (OHRQoL).」

「An additional 2-3 points were assigned to the four dimensions (oral function, orofacial pain, orofacial appearance, and psychological impact).」

「A complete denture patient's prosthetic rehabilitation should never be confined to the replacement of lost teeth; rather, the ultimate goal should be the restoration of oral functions and aesthetics.」

「Bone quality, volume, height and width all play a pivotal role in dental implant stability, success and survival.」

「Sites with poorer bone quality and lack of bone volume may statistically affect implant failure rates.」

「Overall implant survival was 97% and was not associated with implant length (P=0.930), implant diameter (P=0.704), jaw location (P=0.545), implant position (P=0.450), local bone quality (P=0.398), previous bone augmentation surgery (P=0.617), or patient-related factors including osteoporosis (P=0.661), age (P=0.575), or diabetes mellitus (P=0.928).」

「Availability of adequate quantity and quality of bone is prerequisite for longevity and survival of endosseous dental implants.」

「This study evaluated the success and survival rate of sandblasted and acid-etched dental implants according to the patient's bone quality.」

「There was no significant difference among MBL and bone quality, implant type, angle of abutment, prosthodontic type, crown-to-implant ratio, gender, and age of the patients (P > 0.05).」

「For dental implant success, experimentally established thresholds should limit bone stresses and strains.」

「Dental implants shorter than 8 mm, called short dental implants (SDIs), have been considered to have a lower success rate than standard length implants.」

「The survival rate of dental implants is markedly influenced by the host bone quality and quantity of the jawbone.」

「Insufficient bone volume, unfavorable bone quality, periodontal bone loss, and systemic conditions, including osteopenia/osteoporosis and diabetes mellitus, have been associated with implant failure.」

「Key words:Bone grafting, dental implant, osseointegration, risk factor, survival rate, treatment outcome.」

「A total of 40 patients requiring dental implant placement with bone augmentation were included in this prospective study.」

「The parameters such as (i) success and survival of dental implants (ii) peri-implant clinical parameters after prosthetic loading at 1 year, 2 year and 3 year follow up (iii) resorption of alveolar ridge regenerated before placement of dental implants and after placement of dental implants were assessed.」

「This review aims to evaluate recent research on various techniques and materials used in implant dentistry, focusing on short implants, bone augmentation, sinus lift procedures, and soft tissue management.」

「Contemporary dental implant therapy has flourished in recent years thanks in large part to advances made in bone augmentation capabilities.」

「The defective site requires bone grafting as an initial surgical intervention before dental implant placement.」

「Bone augmentation procedures aim to regenerate the deficient alveolar ridge to properly place dental implants that are completely surrounded by bone.」

「The iliac crest is a frequently used donor location in oral and maxillofacial procedures for bone augmentation in order to restore jaw deformities brought on by trauma or pathological diseases prior to the placement of dental implants.」

「Bone graft materials are more and more frequently used in dentistry for improving the periodontal support and for creating a bone support favorable for the insertion of dental implants.」

「Bone augmentation is a necessity for atrophied alveolar ridge prior to dental implant placement.」

「Majority (77.0%) agreed they would undertake a root canal treatment on a pregnant patient with all respondents in restorative dentistry, prosthodontics, periodontics, and pedodontics in the affirmative while all in oral pathology would refuse to do such (P = 0.0001).」

「Half of the teeth (49.2%) which needed orthodontic treatment had history of root canal treatment while 46% needed primary or secondary endodontic treatment.」

「To evaluate the clinical outcome of root canal treatment by obturation technique, root canal filling quality, and tooth- and patient-related variables.」

「Some of the existing abutment teeth were extracted, others presented previously performed root canal treatments and others required endodontic treatment.」

「Subsequent to orthodontic and endodontic treatment, prosthodontic rehabilitation was performed.」

「The first right primary molar had received a root canal treatment 18 months prior.」

「This paper discusses, using the available literature, the maintenance of optimal coronal seal and coronal integrity during and after root canal treatment.」

「This focussed review aims to recount the OHRQoL of patients following nonsurgical root canal treatment and surgical endodontic treatment, with a specific focus on the minimal important difference (MID; the minimum score changes of an outcome instrument for a patient to register a clinically significant change in their OHRQoL and/or oral condition) and the methods used to determine it.」

「A careful survey of the existing literature reveals that most review articles only focus on the application of BAG in root canal treatment, endodontic treatment, implant restoration, and bone regeneration, and there is a conspicuous scarcity of comprehensive reviews dedicated to the application of BAG in the remineralization of dental hard tissue.」

「The data from 901 patients who received root canal treatment in a molar tooth were examined regarding c-shaped root canals, their treatment and their status one year post op.」

「Implant-supported full-mouth rehabilitation has emerged as an advanced solution, leveraging strategically placed dental implants to support fixed prostheses that mimic natural teeth in appearance and function.」

「In addition to restoring oral function, stable aesthetic outcome has become the goal of oral implant therapy.」

「Clinical and radiographic evaluation suggested satisfactory restoration of the mandibular angle contour and adequate bone height for subsequent dental implant placement in patients.」

「A prospective, randomized, single-blind trial was conducted in patients undergoing dental implant restoration in our hospital.」

「in an effort to identify and validate which animal models are best suited for dental implant research, we used multiscale analyses to examine tooth extraction wound healing in a well-accepted model, the Yucatan mini pig and a more controversial model, the laboratory mouse. first molar extractions were performed in adult, skeletally mature mini pigs and mice.」

「Branemark's original dental implant technique included a mesiobuccal flap and a two-stage approach, needing 6-8 months of recovery following extraction, sterile conditions, machined titanium implants, 3-6 months without stress for osseointegration, and a detachable temporary prosthesis.」

「Furthermore, the height and width of the fibula and the thickness of cortical bone is suitable for dental implants.」

「Nonvascularized bone reconstruction and oral rehabilitation using fixed prosthesis with dental implants enabled recovery of appearance and mastication function.」

「At 12 months, statistically significant (p < 0.05) recession coverage (MRC 94.71%) and improvement of aesthetics (pink aesthetic score) was obtained at all implants.」

「FFF reconstruction permits dependable, implant-supported rehabilitation, but multisegment osteotomies and prolonged surgery heighten soft-tissue morbidity, which in turn constrains both MIO and appearance.」

「We envision that it would be an ideal alternative for patients who pursue esthetic orthodontic treatment but were not likely to take lingual appliances or clear aligners.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「Clear aligners have become a treatment alternative to metal brackets in recent years due to the advantages of aesthetics, comfort, and oral health improvement.」

「To evaluate the facial aesthetic effects of orthodontic treatment performed with clear aligners and to compare it to an untreated control group, on lower third facial ageing in adult patients through the use of the Wrinkle Severity Rating Scale (WSRS) at the beginning (T0) and at the end (T1) of the study period.」

「The greatest demand for orthodontic treatments comes from women, as they pay more attention to aesthetics, which makes the clear aligners the most common choice.」

「With the advent of advanced appliances such as ceramic brackets, lingual braces, and clear aligners, alongside a growing emphasis on aesthetics and self-image, orthodontic care has become increasingly relevant for adults.」

「There was no association between sex, previous orthodontic treatment history, satisfaction with own dental appearance and potential interest in treatment and aligner visibility and willingness-to-pay.」

「The precision of a 3D-printed dental model mainly relied on characteristics of photocurable resin, the resolution of light source and the exposure condition, which determined the eventual shape of the molded clear aligner and thus the orthodontic treatment efficacy.」

「The introduction, in the late years of the last century, of clear aligners therapy (CAT) has drastically changed the approach' perspective to orthodontic treatment.」

「Recently, clear aligners have become a popular choice for orthodontic treatment, particularly among adults.」

「重度牙周炎发展到后期可能出现牙髓炎症和坏死，需要牙周牙髓联合治疗；还可能出现牙齿扇形移位，需要联合进行正畸治疗。本文介绍1例通过牙周、牙髓、正畸、种植多学科联合治疗的重度牙周炎，纵向观察6年，成功改善了患者的牙周状态，重建了牙周支持组织，改善了咬合关系，达到长期稳定、良好的牙周治疗效果。.」

「Between 2004 and 2019, 29.3% (1564 of 5229) of teeth replaced by dental implants at UNC School of Dentistry had undergone root canal treatment, with the mandibular first molar being the most commonly replaced tooth.」

「These teeth are subjected to the same disturbances as normal ones, such as dental trauma, dental caries and periodontal disease, all of which are independent of severe dental resorption.」

「The conventional methods of restoring teeth, including bridges and removable dentures, may result in progress of periodontal disease or even the creation of local source of general infection.」

「Via the aid of radiographic examination, the tooth that had an angular bony defect and apical lesion was diagnosed as having deep caries and chronic periodontitis with a poor prognosis.」

「Although clear aligners may limit axial tooth movement, OE remains a minimally invasive, cost-effective alternative in both restorative and implant dentistry.」

「In such cases, endodontic treatment is not indicated to enhance periodontal treatment results.」

「Although dental trauma injuries and caries are more frequently encountered in a younger population, tooth loss because of periodontal disease occurs in the older population.」

「The occurrence of bacteria common to both sites in this patient further supports the proposition that periodontal disease is the definitive source of root canal infections.」

「Although dental trauma injuries and caries are more frequently encountered in a younger population, tooth loss because of periodontal disease occurs in the older population.」

「Although clear aligners may limit axial tooth movement, OE remains a minimally invasive, cost-effective alternative in both restorative and implant dentistry.」

「The initial phase involved periodontal, orthodontic, and implant treatment.」

「Other applications of bioactive glasses in dentistry include their usage in periodontal disease, root canal treatments, maxillofacial surgeries, dental restorations, air abrasions, dental adhesives, enamel remineralization, and dentin hypersensitivity.」

「The replacement of natural teeth that have extreme external apical root resorption, induced by orthodontic treatment, with osseointegrated implants is not justifiable biologically or clinically.」

「The current English literature dealing with "cost-effectiveness" of dental implant therapy versus different alternative treatment modalities, that is, complete and fixed partial dentures, root canal, and periodontal treatment, has been included in this narrative review.」

「This study surveyed the preferences of Ontario, Canada dentists for teeth with apical periodontitis when selecting between retention via root canal treatment (RCT) and extraction without replacement, or replacement with implant-supported crowns (ISC), fixed, or removable partial prostheses.」

「Periodontal, orthodontic, and prosthodontic treatments are extremely useful to improve function and stable periodontal tissue for generalized periodontitis.」

「Following 12 months of orthodontic treatment, the tooth was successfully moved occlusally in conjunction with an 8 mm vertical interdental bone augmentation.」

「Dental implants are regularly placed in patients with a history of periodontitis, even though peri-implant tissues are susceptible to the same host-modulated plaque-induced factors that initiate and sustain periodontitis.」

「Orthodontic treatment does not aggravate or hasten the progression of aggressive periodontitis.」

「Extraction of teeth and immediate dental implant placement has been suggested.」

「Mini dental implants (MDIs) in dentistry are recommended for cases with adequate bone quality and height, but a lack of alveolar bone width.」

「Eleven months after the dental implant surgery, a complete upper denture and a mandibular gingival ceramometal-casting crown were fitted.」

「Four months after bone augmentation, dimensionally sufficient dental implants were inserted and implants-supported prostheses were made 3 months later.」

「Osseointegrated dental implants have become an integral factor in the replacement of missing teeth.」

「Conclusion: Based on this literature review, one-piece ceramic implants achieve osseointegration similar to titanium implants, with a stable MBL or a slight bone gain after an individual initial design depending on crestal remodeling.」

「Dentists providing implant dental treatment need to fully appreciate the legal and clinical issues that are relevant to implant dentistry.」

「Dental implants provide a long-term solution; however, their success depends on a multidisciplinary approach, involving orthodontics, periodontics, prosthodontics, and surgical collaboration.」

「The technique described results in improved appearance and function through definition of the lower third of the face and simultaneous dental implant replacement.」

「The findings emphasize the importance of interdisciplinary treatment of hypodontia, leading to a satisfactory, functional, and long-term fixed prosthodontics using dental implants.」

「Despite successful root canal treatment, if the majority of bone support has been lost from periodontitis, the tooth may have a poor prognosis.」

「The patient was treated with clear aligners, which effectively controlled the strength and direction of orthodontic forces after 3 months of systematic periodontal treatment.」

「Initial periodontal-endodontic treatment was followed by orthodontic and orthognathic surgical therapies.」

「It has shown significant advantages in the orthodontic treatment of periodontal disease, the orthodontic treatment of temporomandibular joint disorder (TMD), integrated approaches with dental implant restoration, and the combined treatment of orthodontics and orthognathic surgery.」

「The prevalence of AP was significantly higher in teeth with inadequate root canal treatment compared with those with adequate treatment, 70.8% and 29.3%, respectively.」

「An increasing number of adult patients are seeking orthodontic treatment to improve their dental appearance.」

「It may occur as a consequence of dental trauma, orthodontic treatment, and bleaching, and occasionally it accompanies periodontal disease.」

「In case 3, 2 years postinjury, pulp necrosis and apical periodontitis occurred, and the tooth was managed with regenerative endodontic treatment consistent with the European Society of Endodontology and the American Association of Endodontists guidelines/recommendations for a regenerative procedure.」

「Patients with periodontal disease often require combined periodontal-orthodontic interventions to restore periodontal health, function, and aesthetics, ensuring both patient satisfaction and long-term stability.」

「As predicted by model one, the probability of absence of periapical lesion 2 years after endodontic treatment was 90% in pulpitis teeth with sever root-canal curvature and adequate root canal fillings, but 51% in teeth with apical periodontitis.」

「We envision that it would be an ideal alternative for patients who pursue esthetic orthodontic treatment but were not likely to take lingual appliances or clear aligners.」

「Proper selection of cases and reasonable design in clear aligner treatment are expected to obtain tooth alignment, good intercuspation, normal overbite and overjet, periodontal health, parallel roots, and to achieve the goal of aesthetic, functional, stable, and healthy orthodontic treatment. 术者诊断设计不当、矫治技术应用失误、正畸治疗后的复发以及患者依从性较差无法配合矫治等原因可导致患者对矫治结果不满意，寻求二次矫治。此类患者通常已减数，或伴牙周、关节、牙体或缺牙等问题，常需多学科联合治疗，二次矫治难度较大，可选方案受限。无托槽隐形矫治舒适美观，具备数字化精准化程度高、可个性化排牙模拟矫治后终末状态等特点，使其在失败病例的二次矫治中具有一定优势。本文通过展示无托槽隐形矫治在二次矫治病例中的应用实例，对矫治设计和监控细节进行讨论和总结。建议医师在接诊前利用无托槽隐形矫治难度评估工具对患者情况进行评估，接诊自身诊疗能力范围内的病例，以获得满意的矫治疗效。无托槽隐形矫治技术治疗减数病例的成功关键在于诊断正确，选对病例。在方案设计上，二次矫治应注意前牙转矩的恢复，利用推磨牙向后获得间隙，做好垂直向控制，改善后牙咬合关系。在无托槽隐形矫治中正确选择、谨慎纳入、合理设计，有望在二次矫治的疑难病例中获得牙排列整齐、尖窝交错、覆(牙合)覆盖正常、牙周健康、牙根平行的矫治效果，达到美观、功能、稳定、健康的矫治目标。.」

「Clear aligners have become a treatment alternative to metal brackets in recent years due to the advantages of aesthetics, comfort, and oral health improvement.」

「To evaluate the facial aesthetic effects of orthodontic treatment performed with clear aligners and to compare it to an untreated control group, on lower third facial ageing in adult patients through the use of the Wrinkle Severity Rating Scale (WSRS) at the beginning (T0) and at the end (T1) of the study period.」

「The greatest demand for orthodontic treatments comes from women, as they pay more attention to aesthetics, which makes the clear aligners the most common choice.」

「There was no association between sex, previous orthodontic treatment history, satisfaction with own dental appearance and potential interest in treatment and aligner visibility and willingness-to-pay.」

「With the advent of advanced appliances such as ceramic brackets, lingual braces, and clear aligners, alongside a growing emphasis on aesthetics and self-image, orthodontic care has become increasingly relevant for adults.」

「The precision of a 3D-printed dental model mainly relied on characteristics of photocurable resin, the resolution of light source and the exposure condition, which determined the eventual shape of the molded clear aligner and thus the orthodontic treatment efficacy.」

「One of the motivating reasons for patients to use clear aligner therapy is to improve their esthetic appearance, which typically is the same motivation for teeth bleaching, thus a combination of the two treatments may be desirable.」

「Recently, clear aligners have become a popular choice for orthodontic treatment, particularly among adults.」

「For tooth loss due to periodontal disease, higher ORs were found in patients who were on anti-depressants (OR = 4.28) and patients who had an initial diagnosis of Stage III/IV periodontitis (OR = 2.66).」

「Aggressive periodontitis (AgP) is a severe periodontal disease that causes early tooth loss in healthy young patients.」

「The conventional methods of restoring teeth, including bridges and removable dentures, may result in progress of periodontal disease or even the creation of local source of general infection.」

「The MSFA could be considered the gold standard procedure for bone-guided regeneration as it provides suitable functional and aesthetic solutions to alveolar ridge atrophy due to tooth loss.」

「The specialist dentist SSO for Reconstructive Dentistry is the expert for the rehabilitation of teeth after tooth loss.」

「This case report is of a 31-year-old female who presented with splinted and faulty metalloceramic prosthesis on maxillary anterior teeth, which was responsible for localised periodontal disease and poor aesthetics.」

「A complex implant-perio-prosthodontic case of a 54-year-old man affected by meningeal melanomatosis with a history of generalized severe chronic periodontitis was recruited.」

「Patients with missing anterior teeth lack an impressive appearance aesthetically and as well as psychologically.」

「A 38-year-old, otherwise healthy male with compromised function and esthetics, PTM, periodontal disease, and missing teeth presented to our clinic.」

「Comprehensive intraoral and radiological examinations assessed caries lesions, missing teeth, filled teeth, periodontal disease, denture usage, and the prevalence of apical osteitis, soft tissue lesions, and intraosseous lesions.」

「Periodontal disease (periodontitis) is a chronic inflammatory condition initiated by microbial infection that leads to gingival tissue destruction and alveolar bone resorption.」

「Periodontal disease is an inflammatory condition caused by polymicrobial infection.」

「Periodontal disease is one of the most common oral diseases causing inflammation in the soft and hard tissues of the periodontium and is initiated by bacteria that induce a host response.」

「Periodontal disease is highly prevalent, with 90% of the world population affected by either periodontitis or its preceding condition, gingivitis.」

「Periodontal disease is a chronic inflammatory disease that results in the breakdown of the tooth-supporting tissues, and can ultimately lead to resorption of the alveolar bone.」

「Periodontal disease (PD) is a common dental disease associated with the interaction between dysbiotic oral microbiota and host immunity.」

「Periodontal disease is a disease of tooth-supporting tissues.」

「Periodontal disease parameters, including bacterial colonization/infection, immune response, inflammation, alveolar bone resorption, and systemic spread, were assessed post-euthanasia.」

「Periodontal disease is a pathological condition that involves inflammation of the tooth supporting structures.」

「Periodontal disease is caused by subgingival bacteria that adversely affect the host immune system and create and maintain unmitigated inflammation in gingival and periodontal tissues.」

「In case 2, a 29-year-old woman reported discomfort during occlusal loading after a root canal treatment and a coronal restoration of the mandibular right first molar.」

「Chimpanzees (Pan troglodytes) with teeth severely damaged by dental caries and/or periodontal disease are often managed with medication and/or tooth extraction.」

「Mandibular first molars are the most commonly extracted teeth due to dental caries and periodontal disease.」

「The reasons for tooth extraction were assigned to different causes, ie, dental caries, periodontal disease, eruption problems, trauma, orthodontics, failed root canal treatment, and others.」

「While emergency dental care, tooth extraction and restorative care for acute pain due to carious lesions are covered in most responding countries, root canal treatment, periodontal care and prosthetic restoration often require cost-sharing or are entirely excluded from the benefit basket.」

「Tooth extraction is indicated in cases such as chronic periodontal disease, abscess, root caries, root stumps, fractured teeth, and failed root canal treatments with the persistence of periapical cysts or granulomas, impacted teeth, or to facilitate orthodontic or prosthodontic rehabilitation.」

「List the indications for tooth extraction, know indications for potential oral/dental treatments beyond subgingival and supragingival scaling and polishing or extraction, and determine whether the professional treatment that may be indicated, such as root canal treatment or mass resection of oral tissues, requires referral for specialist-level expertise and instrumentation.」

「Substantial loss of tooth structure was the leading cause of extraction of root canal-treated teeth, followed by vertical root fracture and periodontal disease.」

「Chi-square and multivariable logistic regression analyses were performed to investigate associations with risk factors such as gender, tooth type, root canal treatment adequacy, final restoration status, dental caries, and periodontal disease.」

「The good prognosis of root canal treatment for teeth with acute symptoms supports recommending dentists to attempt root canal treatment rather than opting for tooth extraction.」

「Orthodontic treatment does not aggravate or hasten the progression of aggressive periodontitis.」

「Periodontal disease often results in severely bony defects around the teeth and leads to eventual extraction.」

「Periodontal, orthodontic, and prosthodontic treatments are extremely useful to improve function and stable periodontal tissue for generalized periodontitis.」

「A dental implant is a surgical fixture that forms an interface with the jaw bone to support dental prostheses, including crowns, bridges, dentures, and facial prostheses; it can also act as an orthodontic anchor.」

「After performing cause-related therapy, periodontal regenerative surgery, pre-orthodontic posterior implant placement, and orthodontic treatment involving anterior implant placement with papilla reconstruction, the patient achieved full-mouth rehabilitation and improvement of dental and smile esthetics.」

「Approaching bone defects of jaws treatments, hard and soft tissue augmentation could be considered as a goal for clinicians when performing dental implant placement.」

「They report the 7-year treatment outcomes of the patient after periodontal regenerative and comprehensive orthodontic therapies for functional recovery with implant prosthodontics.」

「The conventional methods of restoring teeth, including bridges and removable dentures, may result in progress of periodontal disease or even the creation of local source of general infection.」

「It has shown significant advantages in the orthodontic treatment of periodontal disease, the orthodontic treatment of temporomandibular joint disorder (TMD), integrated approaches with dental implant restoration, and the combined treatment of orthodontics and orthognathic surgery.」

「Dental implants are regularly placed in patients with a history of periodontitis, even though peri-implant tissues are susceptible to the same host-modulated plaque-induced factors that initiate and sustain periodontitis.」