現代美學牙醫診所

「To ensure the harmonious appearance of the restoration and the natural tooth and to obtain the ideal hard and soft tissue structure, clinicians should have a clear understanding of the factors that influence the success of aesthetics and apply different technique accordingly.」

「This case illustrates that dental implant restoration in the anterior esthetic zone can effectively address functional and esthetic challenges, leading to high patient satisfaction with the final restoration's natural appearance.」

「Due to the excellent restoration of masticatory function, satisfaction on aesthetics and other superiorities, dental implants represent an effective method to resolve tooth losing and damaging.」

「They expected dental implants to restore the patients' appearance, functions, and quality of life to absolute normality.」

「Dental implants are a common treatment for the loss of teeth.」

「Implant mechanical complications, including screw loosening, can influence dental implant success.」

「Conclusion : The use of dental implants to rehabilitate the edentulous cleft area is an excellent option.」

「Successful dental implant therapy in the maxillary anterior dentition requires meticulous attention to surgical and prosthodontic measures.」

「The development of clinical implant dentistry was intensively affected by dental implant design improvement and innovation, which brought about new concept, even milestone-like changes of clinical protocol.」

「Papilla fill adjacent to a single dental implant appears to depend upon the clinical attachment level of the neighboring tooth.」

「Background and Clinical Significance: Dental implants are widely used; however, tooth extraction often results in alveolar bone loss and gingival recession, necessitating bone and connective tissue reconstruction, especially in the esthetic anterior regions.」

「A treatment for replacing missing teeth, a dental implant can last for the long term and requires adequate care and hygiene compared to fixed partial dentures (FPDs).」

「Periodontal probing around natural teeth and dental implants remains an efficient and non-invasive method to diagnose loss of attachment, determine presence of diseases, monitor marginal recession, and evaluate positive treatment outcomes.」

「They can cause inflammation of the adjacent tooth-supporting (periodontal) tissues, leading to destructive periodontal disease and tooth loss.」

「Dental implant placement is a widely used treatment that provides functional and esthetic resolution for patients suffering from tooth loss.」

「In patients with advanced periodontal disease, pathological tooth migration may occur, which may require subsequent orthodontic treatment for both aesthetic and functional purposes.」

「The control of the periodontal disease before implant insertion in patients with severe chronic periodontitis is of paramount importance, as well as a regular maintenance program is essential for the health of the periodontal and peri-implant tissues.」

「Periodontitis is a complex multifactorial disease that can lead to destruction of tooth supporting tissues and subsequent tooth loss.」

「Substantial loss of tooth structure was the leading cause of extraction of root canal-treated teeth, followed by vertical root fracture and periodontal disease.」

「A patient who is interested in replacing missing teeth may be a candidate for dentures, implants, or a combination of these.」

「Dental implants restore function to near normal in partially or completely edentulous patients.」

「Dental implants are a common treatment for the loss of teeth.」

「Dental implants provide completely edentulous and partial edentulous patients the function and esthetics they had with natural dentition.」

「Dentists providing implant dental treatment need to fully appreciate the legal and clinical issues that are relevant to implant dentistry.」

「Systematic reviews of literature over the period between 2008 and 2017 are discussed regarding clinical evidence for the factors affecting survival and failure of dental implants.」

「Since 1970s, a lot of effort has been devoted toward the development of dental implants.」

「Many options exist to replace missing teeth but dental implants have become one of the most used biomaterial to replace one (or more) missing tooth over the last decades.」

「A dental implant is a medical device used to functionally and aesthetically rehabilitate the lack of one or more teeth, allowing the support of a prosthetic substitute through direct bone support [...].」

「Tooth loss is very a very common problem; therefore, the use of dental implants is also a common practice.」

「As well as reviewing the history of dental implants, this narrative review will discuss the merits and successful placement of tissue-level verses bone-level implants.」

「Between 2004 and 2019, 29.3% (1564 of 5229) of teeth replaced by dental implants at UNC School of Dentistry had undergone root canal treatment, with the mandibular first molar being the most commonly replaced tooth.」

「Comprehensive case assessment, evaluation of all endodontic options, and risk assessment for caries and periodontal disease are always necessary when choosing the optimal treatment for a patient when initial root canal treatment has failed to heal.」

「Dental implant system-assisted IR can effectively preserve "drifted" natural PHT in patients with stage III/IV periodontitis.」

「The current English literature dealing with "cost-effectiveness" of dental implant therapy versus different alternative treatment modalities, that is, complete and fixed partial dentures, root canal, and periodontal treatment, has been included in this narrative review.」

「Other applications of bioactive glasses in dentistry include their usage in periodontal disease, root canal treatments, maxillofacial surgeries, dental restorations, air abrasions, dental adhesives, enamel remineralization, and dentin hypersensitivity.」

「The patient underwent a initial periodontal therapy, periodontal surgery, endodontic treatment, implant treatment, prosthodontic treatment, soft tissue augmentation procedures during the second stage of implant surgery, and supportive periodontal therapy.」

「Other treatment options that aim to save compromised or diseased teeth such as endodontic treatment, periodontal treatment, intentional replantation, and autotransplantation should be considered on an individual basis.」

「Other treatment options that aim to save compromised or diseased teeth such as endodontic treatment, periodontal treatment, intentional replantation, and autotransplantation should be considered on an individual basis.」

「Prosthodontic treatment was involved with the highest number 54.5%, followed by dental implants 17.7%, and endodontics 11.6%.」

「Extensive orthodontically induced dental resorption are not an indication for endodontic treatment.」

「Between 2004 and 2019, 29.3% (1564 of 5229) of teeth replaced by dental implants at UNC School of Dentistry had undergone root canal treatment, with the mandibular first molar being the most commonly replaced tooth.」

「Comprehensive case assessment, evaluation of all endodontic options, and risk assessment for caries and periodontal disease are always necessary when choosing the optimal treatment for a patient when initial root canal treatment has failed to heal.」

「Dental implant system-assisted IR can effectively preserve "drifted" natural PHT in patients with stage III/IV periodontitis.」

「The current English literature dealing with "cost-effectiveness" of dental implant therapy versus different alternative treatment modalities, that is, complete and fixed partial dentures, root canal, and periodontal treatment, has been included in this narrative review.」

「Other applications of bioactive glasses in dentistry include their usage in periodontal disease, root canal treatments, maxillofacial surgeries, dental restorations, air abrasions, dental adhesives, enamel remineralization, and dentin hypersensitivity.」

「The patient underwent a initial periodontal therapy, periodontal surgery, endodontic treatment, implant treatment, prosthodontic treatment, soft tissue augmentation procedures during the second stage of implant surgery, and supportive periodontal therapy.」

「Other treatment options that aim to save compromised or diseased teeth such as endodontic treatment, periodontal treatment, intentional replantation, and autotransplantation should be considered on an individual basis.」

「Other treatment options that aim to save compromised or diseased teeth such as endodontic treatment, periodontal treatment, intentional replantation, and autotransplantation should be considered on an individual basis.」

「Prosthodontic treatment was involved with the highest number 54.5%, followed by dental implants 17.7%, and endodontics 11.6%.」

「Extensive orthodontically induced dental resorption are not an indication for endodontic treatment.」

「An increasing number of adult patients are seeking orthodontic treatment to improve their dental appearance.」

「Implants were connected to lateral incisors with provisional restorations, and orthodontic treatment was initiated following digital set-ups incorporating implants into the overall strategy.」

「The initial phase involved periodontal, orthodontic, and implant treatment.」

「Orthodontic treatment does not aggravate or hasten the progression of aggressive periodontitis.」

「It has shown significant advantages in the orthodontic treatment of periodontal disease, the orthodontic treatment of temporomandibular joint disorder (TMD), integrated approaches with dental implant restoration, and the combined treatment of orthodontics and orthognathic surgery.」

「In case of dental malocclusion accompanied by periodontal disease, the utilization of titanium implants for rectifying dental arch deformities without the use of orthodontic brackets, devoid of orthodontic brackets, has demonstrated notable efficacy in alleviating patients' periodontal discomfort, their oral hygiene, and dental functionality.」

「Periodontal, orthodontic, and prosthodontic treatments are extremely useful to improve function and stable periodontal tissue for generalized periodontitis.」

「Following 12 months of orthodontic treatment, the tooth was successfully moved occlusally in conjunction with an 8 mm vertical interdental bone augmentation.」

「The replacement of natural teeth that have extreme external apical root resorption, induced by orthodontic treatment, with osseointegrated implants is not justifiable biologically or clinically.」

「After orthodontic treatment, staged guided bone regeneration was performed and dental implants were placed in the severely resorbed maxillary anterior ridge.」

「The survival rates following root-end surgery range from 48% to 93%, with failure of periapical healing associated with root and crown fracture, being the predominant reasons for tooth extraction.」

「The high survival rate of endosseous implants has also had a significant impact on the way clinicians think about the best treatment for teeth requiring endodontic therapy.」

「A root canal treatment and an all-ceramic crown restoration for tooth #36 were performed.」

「In case 2, a 29-year-old woman reported discomfort during occlusal loading after a root canal treatment and a coronal restoration of the mandibular right first molar.」

「The good prognosis of root canal treatment for teeth with acute symptoms supports recommending dentists to attempt root canal treatment rather than opting for tooth extraction.」

「Therefore, the prognosis of root canal treatment in these cases has been reported poor, and the dentist will offer a plan for possible treatments, including tooth extraction or apical surgery.」

「In Case 2, a 48-year-old man presented with a maxillary left central incisor that had previously undergone root canal treatment and exhibited severe coronal dentin loss beneath an old crown.」

「The clinical and radiographic evaluation revealed severe pain and a periapical lesion from the previous root canal treatment.」

「Coronectomy, a surgical procedure involving intentional crown removal with root retention of mandibular third molars at high risk of inferior alveolar nerve injury, represents a validated nerve-sparing alternative to complete extraction.」

「Untoward events were defined as NS-RCT, tooth extraction, retreatment of root canal, or apicoectomy as defined by the Code on Dental Procedures and Nomenclature.」

「To provide a reference basis for clinical selection of a reasonable and effective root canal treatment by comparing the short-term clinical efficacy of three root canal filling methods in the treatment of chronic periapical inflammation.」

「Endodontic treatment aims to eradicate both microbial infection and inflammatory processes within the root canal space as well as in the periapical (PA) region of the tooth.」

「The successful treatment of both primary and secondary endodontic infections involves effective eradication of the causative microorganisms during root canal treatment procedures.」

「The goal of endodontic treatment is to remove infected content from the root canal system to allow the healing of a pre-existing periapical lesion or to prevent infection of the periradicular tissues.」

「Background Considering the importance of irrigation in dental root canal treatment, there is an urgent need to find a risk-free bioactive and antibacterial endodontic solution.」

「Furthermore, convincing evidence supports that successful root canal treatment has a beneficial impact on systemic health by reducing the inflammatory burden, thereby dismissing the misconceptions of focal infection theory.」

「Root canal treatment will not always be required as some cases can be managed conservatively.」

「In conclusion, if root canal treatment failure due to leakage through cracks, fractures or restoration margin are excluded, the remaining cases may represent localized residual infection and inflammation at the periapex that should be amenable to predictable management with the aid of modern root-end surgery.」

「During the healing of the radicular cyst, the infected tooth should be treated by extraction or root canal treatment completed by surgical intervention.」

「Unfinished root canal treatment (RCT) was the major risk factor for hospitalisation in 16 (27 %) of the 60 cases (p = .0065).」

「Interappointment pain is almost exclusively due to the development of acute inflammation at the periradicular tissues in response to an increase in the intensity of injury coming from the root canal system.」

「To provide a reference basis for clinical selection of a reasonable and effective root canal treatment by comparing the short-term clinical efficacy of three root canal filling methods in the treatment of chronic periapical inflammation.」

「The study included only systematic reviews of clinical trials with or without meta-analyses evaluating effectiveness of medications in reducing pain after non-surgical endodontic treatment.」

「Root canal treatment will not always be required as some cases can be managed conservatively.」

「Patient 1 underwent root canal treatment on teeth 21 and 43 over a 3-year period.」

「Human clinical trials studies in English language with at least 10 patients with mature or immature permanent teeth with pulpitis characterized by spontaneous pain in each arm (i.e., root canal treatment [RCT] and pulpotomy) at the end of the study, comparing the patient- (Primary: survival, pain, tenderness, swelling assessed by clinical history, clinical examination, and pain scales; Secondary: tooth function, need for further intervention, adverse effects; OHRQoL using a validated questionnaire) and clinical-reported outcomes (Primary: emerging apical radiolucency as per intraoral periapical radiograph or limited FOV CBCT scan; Secondary: radiological evidence of continued root formation and presence of sinus tract).」

「The ultimate goal of an endodontic treatment is to eliminate infection, thoroughly clean and disinfect the root canal system, and prevent reinfection.」

「The debilitating orofacial pain began after initial nonsurgical root canal treatment of the maxillary molar 3 years before presenting to our clinic.」

「Regenerative endodontic treatment (RET) presents a promising alternative, aiming to eliminate infection while fostering root development and tooth vitality.」

「The purpose of this systematic review was to compare the healing rate and post-obturation pain of single- versus multiple-visit root canal treatment for teeth with infected root canals.」

「Dental root canal treatment is required when dental caries progress to infection of the dental pulp.」

「Dental caries, pulpal necrosis, trauma, and periodontal diseases can result in dental infections which could have severe consequences that affect both soft and hard tissues of the oral cavity.」

「Inflammation in pulp tissues caused by dental caries will lead to periapical granulomas, bone erosion, loss of the tooth, and severe pain.」

「Impact statement Dental pulp exposure from dental caries, wounds, or deep cavity preparation can cause pain and infection, which may lead to root canal treatment or tooth extraction.」

「It is foremost to understand how the biofilm formed by root canal bacteria resists endodontic treatment measures.」

「Dental caries (DC)-induced pulp infections usually undergo the common endodontic treatment, root canal therapy (RCT).」

「Dental caries is the most common oral disease worldwide, and it is estimated to affect 2.3 billion people, with at least 530 million of them being schoolchildren with decayed primary teeth.」

「If dental caries (or tooth decay) progresses without intervention, the infection will advance through the dentine leading to severe pulpal inflammation (irreversible pulpitis) and pulp death.」

「Dental caries may lead to endodontic disease, where the bacterial infection progresses to the root canal system of the tooth, leading to periapical inflammation, bone erosion, severe pain, and tooth loss.」

「The invasion of the root canal system (RCS) by pathogenic microorganisms, compounded by the rising concern of antimicrobial resistance (AMR), emphasizes the necessity for a culture-driven and evidence-based approach to antibiotic selection in pediatric endodontics, wherein the therapeutic efficacy of root canal treatment is inherently dependent on the comprehensive elimination of endodontic microbiota.」

「The aims of this study were to evaluate the sensitivity of the ATP detection method and the specificity of this assay for viable cells and to compare the ATP and culture methods from root canal samples of patients undergoing endodontic treatment.」

「By completing an optimal root canal treatment, endodontic therapy aims to repair the damaged periapical area by removing microorganisms and their by-products from the infected root canal space.」

「Endodontic treatment is one of the main dental treatments to manage inflamed or infected root canal systems of teeth.」

「Complete sterilization of an infected root canal is an important challenge in endodontic treatment.」

「The subsequent root canal treatment is not able to remove all the pathogens, and a small number of viable bacteria remain in the dentine tubules, which must be sealed by endodontic sealers.」

「Furthermore, convincing evidence supports that successful root canal treatment has a beneficial impact on systemic health by reducing the inflammatory burden, thereby dismissing the misconceptions of focal infection theory.」

「The best way to prepare the tooth for obturation using hydraulic calcium silicate cement (HCSC) sealers and gutta-percha, thus guiding clinicians on a matched irrigation-obturation strategy for optimized root canal treatment was investigated.」

「Conventionally, root canal treatment is performed when the dental pulp is severely damaged or lost due to dental trauma or bacterial endodontic infections.」

「One may view root canal treatment as having two important procedural parts: (i) gaining access to the root canal and (ii) achieving clean root canals to remove the necrotic/infected or irreversibly inflamed tissues and then fill the space that was occupied by the pulp tissue and subsequently enlarged during cleaning and shaping, which should result in two key long-term outcomes: (i) healing of periradicular periodontitis and (ii) survival/retention of the tooth.」

「Dental root canal treatment is required when dental caries progress to infection of the dental pulp.」

「On the basis of the information available from insurance claims data, this study shows that the long-term survival rates of initial endodontic therapy are adversely affected by the delayed placement of the final restoration and full coverage crown.」

「This study aimed to quantify the longevity of teeth treated endodontically in general dentistry practices and test the hypothesis that longevity significantly differed by the patient's age, gender, dental insurance, geographic region, and placement of a crown and/or other restoration soon after root canal treatment (RCT).」

「This investigation revealed that the tooth retention rate of endodontically treated teeth was 96.2% after initial root canal treatment, 92.4% for nonsurgical re-treatment, and 97.8% for surgical re-treatment.」

「The survival rate was significantly higher (97%) for cracked teeth receiving a full crown after endodontic treatment compared to teeth restored with either a composite filling or composite crown.」

「Under the premise of high quality root canal treatment and standard restoration treatment, the abutment teeth, whether are restored by glass fiber post and core, cast metal post and core or without post, have a higher survival rate over 5 years of observation period and complications especially root fracture still should attract the necessary attention.」

「There are currently no prospective studies evaluating the long-term outcomes of non-surgical root canal treatments beyond 5 years, both in terms of treatment success and tooth preservation, and identifying factors predictive of treatment outcome.」

「The aim of the study was to evaluate the possible relationship between the quality of restorative crown of the tooth, obturation of the root canal and the periapical status of the teeth that were subjected to endodontic treatment.」

「This retrospective study aimed to investigate the 10-year survival rate of teeth treated in a public endodontic specialist clinic.」

「Therefore, it is of interest to compare long- term outcomes of endodontic treatment versus implant-supported crowns in 412 teeth from 378 patients over 10 years.」

「Evidence shows a clear hierarchy: indirect restorations, particularly full-coverage crowns (FCCs), demonstrate superior success and survival rates due to their fracture resistance and effective stress distribution.」

「The result of our study indicates that single visit root canal treatment is a safe, effective and practical method of treatment of an endodontically involved tooth both in vital and non vital cases when applied in appropriate situation.」

「An electronic search was conducted to identify randomized clinical trials (RCT) investigating postoperative pain in patients who underwent root canal treatments in permanent teeth using PIPS Er: YAG laser-activated irrigation or conventional needle irrigation.」

「The current research results give insight into the incidence of postoperative endodontic pain among the study participants undergoing root canal treatment through single or multiple visit appointments.」

「In root canal treatment, post-operative endodontic pain is considered as a common post-operative complication.」

「This prospective clinical study compares postoperative pain after single-visit, non-surgical root canal treatment of teeth with irreversible pulpitis using two different root canal filling techniques.」

「The predictive models showed that the incidence of post-endodontic pain was significantly lower when the treated tooth was not a molar (P = 0.003), demonstrated periapical radiolucencies (P = 0.003), had no history of previous pain (P = 0.006) or emergency endodontic treatment (P = 0.045) and had no occlusal contact (P < 0.0001).」

「CONCLUSIONS: Single-dose oral medications administered after non-surgical root canal treatments effectively reduce post-endodontic pain.」

「The purpose of this systematic review was to compare the healing rate and post-obturation pain of single- versus multiple-visit root canal treatment for teeth with infected root canals.」

「The aim of this study was to compare the effect of different application techniques of ozone on the prevalence of postendodontic pain in patients undergoing single-visit root canal treatment. hundred eight patients with necrotic pulp in single-rooted teeth and apical periodontitis participated in the trial.」

「Laser technology has revolutionised endodontic treatment by enhancing disinfection, promoting healing, facilitating root canal treatment, improving canal shaping and decreasing pain associated with endodontic treatments.」

「In part 2 of this series, we look at the clinician's role in replacing multiple missing teeth and the associated soft tissues and bone, following severe forms of trauma.」

「In the analysis, a core category was identified as "Transition from tooth loss, to 'Amputation', and to implants - negative and positive trajectories".」

「Dental implants are used to anchor prosthetic teeth and represent the gold standard for replacing missing teeth.」

「There was no significant difference in gender, age, implant, cause of tooth loss, history of hypertension, drinking history, implant diameter, implant length and bone increment surgery between good and poor groups(P＞0.05).」

「A new era in modern dentistry has emerged where tooth loss is no longer an issue as a result of rapid advancements in implantation and alveolar ridge reconstruction.」

「To restore masticatory function and satisfactory aesthetics, missing teeth must be replaced.」

「Young patients with tooth agenesis and with an increased number of missing teeth are more content about the treatment with dental implants than patients with tooth loss.」

「The benefits of choosing fixed partial dentures (FPD) or dental implants were judged to be aesthetics (41.1%) and the feel of one's own teeth (40.1%).」

「Dental implants are being utilized by numerous dentists to replace missing teeth by restoring the function of teeth without compromising the aesthetics.」

「They regarded dental implants as a panacea for all cases of missing teeth, overestimated their functions and longevity, and underestimated the expertise needed to carry out the clinical procedures.」

「While dental implants are increasingly becoming the choice of replacement for missing teeth, the impediments associated with them are progressively emerging too.」

「To assess the clinical effects of various materials and techniques for ARP after tooth extraction compared with extraction alone or other methods of ARP, or both, in patients requiring dental implant placement following healing of extraction sockets.」

「There was no significant difference in gender, age, implant, cause of tooth loss, history of hypertension, drinking history, implant diameter, implant length and bone increment surgery between good and poor groups(P＞0.05).」

「In terms of the effect of missing teeth, greater deviations were observed in models with more extensive tooth loss, particularly at the functional cusp areas, suggesting reduced accuracy in complex occlusal conditions.」

「This study highlights the promising role of AI in enhancing the precision and efficiency of dental implant surgery planning for single tooth defects.」

「Dental implants are used to anchor prosthetic teeth and represent the gold standard for replacing missing teeth.」

「Dental implants are a well-established treatment for replacing missing teeth; however, reports of associated complications are increasing.」

「This case report illustrates how digital dentistry enhances implant placement precision and reliability.」

「Prosthodontics is that branch of dentistry that deals with replacing missing teeth using either fixed or removable appliances in an attempt to simulate natural tooth function.」

「The benefits of choosing fixed partial dentures (FPD) or dental implants were judged to be aesthetics (41.1%) and the feel of one's own teeth (40.1%).」

「To restore intraoral function and improve facial appearance, plastic surgeons transplanted a rib into the maxillary sinus while dental surgeons simultaneously inserted 5 dental implants.」

「In addition to restoring oral function, stable aesthetic outcome has become the goal of oral implant therapy.」

「Treatment efficacy, safety, peri-implant bone resorption, periodontal pocket depth, dental aesthetics (Pink Esthetic Score, PES; White Esthetic Score, WES), masticatory function, oral function recovery, and patient satisfaction were compared between the two groups.」

「The report underscores the transformative potential of implant-supported rehabilitation, highlighting high success rates, patient satisfaction, and the multifaceted benefits of restoring oral function and aesthetics with advanced dental technologies.」

「The technique described results in improved appearance and function through definition of the lower third of the face and simultaneous dental implant replacement.」

「For many years, edentulous patients have had no other option than conventional dentures to reestablish their oral function.」

「Dental implantation has emerged as an efficient substitute for missing teeth, which is essential for restoring oral function and aesthetics.」

「Twenty-one fully edentulous patients received mandibular overdenture retained on a bar connecting two titanium dental implants.」

「There is a lack of consensus on managing resultant bone and soft tissue defects or on restoring oral function and aesthetics following medication-related osteonecrosis of the jaws (MRONJ) lesion healing.」

「The use of dental implants to support full mouth prosthetic rehabilitation for adolescents with ectodermal dysplasia may provide a considerable improvement in function and esthetic compared to conventional removable prosthetic options.」

「This review provides updates on acute conditions affecting the periodontal tissues, including abscesses in the periodontium, necrotizing periodontal diseases and other acute conditions that cause gingival lesions with acute presentation, such as infectious processes not associated with oral bacterial biofilms, mucocutaneous disorders and traumatic and allergic lesions.」

「It has been observed from several oral pathogens that P. gingivalis has received immense attention due to a strong association between Porphyromonas Gingivalis and periodontal disease.」

「Periodontal disease (periodontitis) is a common inflammatory condition affecting the deep, supporting tissues around teeth.」

「Periodontal disease is an inflammatory condition caused by polymicrobial infection.」

「Periodontal disease is a pathological condition that involves inflammation of the tooth supporting structures.」

「In case of dental malocclusion accompanied by periodontal disease, the utilization of titanium implants for rectifying dental arch deformities without the use of orthodontic brackets, devoid of orthodontic brackets, has demonstrated notable efficacy in alleviating patients' periodontal discomfort, their oral hygiene, and dental functionality.」

「Aggressive periodontitis is rapid progression of periodontal disease with severe periodontal breakdown.」

「Periodontal disease is one of the most common oral diseases causing inflammation in the soft and hard tissues of the periodontium and is initiated by bacteria that induce a host response.」

「Periodontal disease is a pathological condition that involves inflammation of the tooth supporting structures.」

「Certain systemic diseases can have a clinical appearance similar to periodontal diseases or exacerbate existing periodontitis/gingivitis and vice versa.」

「Bacteria associated with periodontal disease trigger inflammatory responses in immune cells, which in later stages of the disease cause loss of both soft and hard tissue structures supporting teeth.」

「Periodontal disease (PD) is among the most common infectious diseases in the world, caused by pathogenic bacteria that trigger innate, inflammatory, and adaptive immune responses, leading to the destruction of supporting periodontal tissues and, if untreated, tooth loss.」

「Periodontitis are infectious diseases characterized by immune-mediated destruction of periodontal supporting tissues and tooth loss.」

「Periodontitis is a chronic inflammatory disease characterized by progressive destruction of the periodontal supporting tissues and is strongly associated with shifts in the oral microbiota.」

「According to the new classification proposed by the recent 2017 World Workshop on Periodontal and Peri-implant Diseases and Conditions, periodontitis, necrotizing periodontal diseases, periodontitis as a manifestation of systemic diseases, and systemic diseases or conditions affecting the periodontal supporting tissues, are considered as separate entities.」

「Several microbial agents, mostly bacteria, have been identified as causative factors for periodontal disease.」

「Periodontitis is an inflammatory disease of the oral cavity driven by bacterial dysbiosis that progressively breaks down the tooth-supporting structures.」

「Periodontal diseases are inflammatory diseases caused by oral pathogens around the periodontal supporting tissues, leading to systemic and chronic inflammatory conditions.」

「Although the current treatment of periodontal disease can achieve good control of inflammation, it is difficult to regenerate the periodontal supporting tissues to achieve a satisfactory therapeutic effect.」

「Basically trauma from occlusion has been correlated with periodontal pockets in view of the fact that these would render the periodontal supporting tissues more amenable to the spread of inflammation of biofilm-related periodontal pockets.」

「Periodontitis are infectious diseases characterized by immune-mediated destruction of periodontal supporting tissues and tooth loss.」

「Periodontitis, a bacterial infection leading to the destruction of tooth-supporting tissues, is primarily driven by elevated levels of subgingival microorganisms.」

「Although the current treatment of periodontal disease can achieve good control of inflammation, it is difficult to regenerate the periodontal supporting tissues to achieve a satisfactory therapeutic effect.」

「Obesity is an independent predictive factor for worsened periodontal inflammation, increased onset, progression, severity, and recurrence of infection, as well as delayed wound healing.」

「Periodontal diseases are inflammatory diseases caused by oral pathogens around the periodontal supporting tissues, leading to systemic and chronic inflammatory conditions.」

「According to the new classification proposed by the recent 2017 World Workshop on Periodontal and Peri-implant Diseases and Conditions, periodontitis, necrotizing periodontal diseases, periodontitis as a manifestation of systemic diseases, and systemic diseases or conditions affecting the periodontal supporting tissues, are considered as separate entities.」

「Basically trauma from occlusion has been correlated with periodontal pockets in view of the fact that these would render the periodontal supporting tissues more amenable to the spread of inflammation of biofilm-related periodontal pockets.」

「Periodontal disease (periodontitis) is a common inflammatory condition affecting the deep, supporting tissues around teeth.」

「Periodontitis is the infectious-inflammatory disease of tooth-supporting tissues.」

「Therefore, this finding demonstrated that it was a promising approach for combating anaerobic pathogens with enhanced and selective properties in periodontal diseases, even in other bacteria-induced infections, for future clinical application.」